A glance at black cumin (Nigella sativa) and its active constituent, thymoquinone, in ischemia: a review.
Identifieur interne : 000A28 ( Main/Exploration ); précédent : 000A27; suivant : 000A29A glance at black cumin (Nigella sativa) and its active constituent, thymoquinone, in ischemia: a review.
Auteurs : Zahra Oskouei [Iran] ; Maryam Akaberi [Iran] ; Hossein Hosseinzadeh [Iran]Source :
- Iranian journal of basic medical sciences [ 2008-3866 ] ; 2018.
Abstract
Black cumin (Nigella sativa) belonging to Ranunculaceae family has a long history of medicinal use in various folk and traditional systems of medicine, including Iranian traditional medicine (ITM). These valuable medicinal seeds have been used traditionally against a variety of diseases such as dyspepsia, diabetes, headache, influenza and asthma. In addition, several scientific investigations have reported the therapeutic properties of N. sativa and thymoquinone (TQ), one of the most important constituent of black cumin, for treatment of a large number of diseases, including ischemia. As there is no comprehensive review study about the anti-ischemic activity of black cumin and its mechanism of action, in the current study, we aimed to review the anti-ischemic activities of N. sativa and TQ in different organ-related disorders.
DOI: 10.22038/ijbms.2018.31703.7630
PubMed: 30627362
Affiliations:
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Iran.</nlm:affiliation><country xml:lang="fr">Iran</country><wicri:regionArea>Department of Phamacogenosy, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad</wicri:regionArea><wicri:noRegion>Mashhad</wicri:noRegion></affiliation></author><author><name sortKey="Hosseinzadeh, Hossein" sort="Hosseinzadeh, Hossein" uniqKey="Hosseinzadeh H" first="Hossein" last="Hosseinzadeh">Hossein Hosseinzadeh</name><affiliation wicri:level="1"><nlm:affiliation>Pharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.</nlm:affiliation><country xml:lang="fr">Iran</country><wicri:regionArea>Pharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad</wicri:regionArea><wicri:noRegion>Mashhad</wicri:noRegion></affiliation></author></analytic><series><title level="j">Iranian journal of basic medical sciences</title><idno type="ISSN">2008-3866</idno><imprint><date 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